| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PVT1_0004900 | Exon-Exon | chr8:129001408-129108900 | chr8:127989162-128096654 | 380 nt | 0.4947 |
| hsa_PVT1_0006300 | Exon-Exon | chr8:129021836-129022690 | chr8:128009590-128010444 | 855 nt | 0.3930 |
| hsa_PVT1_0006400 | Intron-Exon-Intron | chr8:129021836-129032965 | chr8:128009590-128020719 | 250 nt | 0.3760 |
| hsa_PVT1_0007600 | Exon-Exon | chr8:129082406-129082518 | chr8:128070160-128070272 | 113 nt | 0.5398 |
| hsa_PVT1_0007700 | Exon-Exon | chr8:129082406-129108900 | chr8:128070160-128096654 | 250 nt | 0.5440 |
| hsa_PVT1_0007900 | Exon-Exon | chr8:129082406-129113499 | chr8:128070160-128101253 | 524 nt | 0.5210 |
| hsa_PVT1_0008500 | Exon-Exon | chr8:129108764-129113499 | chr8:128096518-128101253 | 411 nt | 0.5158 |
| hsa_PVT1_0008700 | Exon-Exon | chr8:129113226-129113499 | chr8:128100980-128101253 | 274 nt | 0.5000 |
| hsa_PVT1_0000400 | Intron-Exon | chr8:128808140-128951922 | chr8:127795894-127939676 | 250 nt | 0.3920 |
| hsa_PVT1_0000500 | Intron-Exon-Intron | chr8:128813945-128894130 | chr8:127801699-127881884 | 250 nt | 0.4120 |
A review of circular RNAs in human development and diseases notes that the circPVT1 is upregulated in gastric cancer and correlates with its function as a sponge for miR-125 [Lee et al. DOI:10.1016/j.biopha.2018.12.052]. Another review on circRNAs in embryogenesis and cancer development reports that the circPVT1 has pro-oncogenic activities in acute myeloid leukemia and head and neck squamous cell carcinoma, with its expression significantly associated with mutant p53 [Di Agostino et al. DOI:10.3389/fcell.2020.00389].