| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_PVT1_0003500 | Intron-Intron | chr8:128981346-128981740 | chr8:127969100-127969494 | 395 nt | 0.4506 |
| hsa_PVT1_0003600 | Intron-Exon-Intron | chr8:128981662-129001537 | chr8:127969416-127989291 | 130 nt | 0.4000 |
| hsa_PVT1_0003700 | Intron-Exon-Intron | chr8:128981662-129022690 | chr8:127969416-128010444 | 508 nt | 0.4488 |
| hsa_PVT1_0003800 | Intron-Exon-Intron | chr8:128988469-129021964 | chr8:127976223-128009718 | 250 nt | 0.3880 |
| hsa_PVT1_0003900 | Intron-Exon-Intron | chr8:128994606-129001537 | chr8:127982360-127989291 | 120 nt | 0.5000 |
| hsa_PVT1_0004000 | Intron-Exon-Intron | chr8:128994606-129022690 | chr8:127982360-128010444 | 133 nt | 0.4135 |
| hsa_PVT1_0004100 | Intron-Intron | chr8:128995540-128995716 | chr8:127983294-127983470 | 177 nt | 0.3955 |
| hsa_PVT1_0004500 | Intron-Exon-Intron | chr8:128996150-129005185 | chr8:127983904-127992939 | 301 nt | 0.5382 |
| hsa_PVT1_0004600 | Intron-Exon-Intron | chr8:128996150-129005297 | chr8:127983904-127993051 | 71 nt | 0.4366 |
| hsa_PVT1_0004700 | Intron-Exon-Intron | chr8:128996150-129022690 | chr8:127983904-128010444 | 127 nt | 0.4173 |
A review of circular RNAs in human development and diseases notes that the circPVT1 is upregulated in gastric cancer and correlates with its function as a sponge for miR-125 [Lee et al. DOI:10.1016/j.biopha.2018.12.052]. Another review on circRNAs in embryogenesis and cancer development reports that the circPVT1 has pro-oncogenic activities in acute myeloid leukemia and head and neck squamous cell carcinoma, with its expression significantly associated with mutant p53 [Di Agostino et al. DOI:10.3389/fcell.2020.00389].