Basic Information
Symbol
circQSOX2
RNA Class
circRNA
Alias
Quiescin Sulfhydryl Oxidase 2
SOXN
QSCN6L1
Neuroblastoma-Derived Sulfhydryl Oxidase
Quiescin Q6 Sulfhydryl Oxidase 2
Quiescin Q6-Like Protein 1
Sulfhydryl Oxidase 2
Quiescin Q6-Like 1
Thiol Oxidase 2
DKFZp762A2013
EC 1.8.3.2
Location (GRCh37)
9:139115609-139118720
UCSC Genome Browser
Location (GRCh38)
9:136223763-136226874
Host gene
QSOX2
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
Tissue/body fluid identification
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_QSOX2_0002500 | Exon-Exon | chr9:139115609-139118720 | chr9:136223763-136226874 | 347 nt | 0.5303 |
Forensic Context
A study in humans demonstrated that circQSOX2, found in peripheral blood mononuclear cells, is a diagnostic marker for schizophrenia, with its low level in patients increasing after antipsychotic treatment and ROC curve analysis showing a sensitivity of 84.31% and specificity of 86.41% [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A study in humans demonstrated that the circQSOX2 is a circular RNA with expression restricted to venous blood samples, and it was included in a target RNA sequencing panel of 135 RNA-SNPs for body fluid identification [Yu et al. DOI:10.1016/j.fsigen.2025.103416].