Basic Information

Symbol
circRAPGEF6
RNA Class
circRNA
Alias
Rap Guanine Nucleotide Exchange Factor 6 RA-GEF-2 PDZ-GEF2 PDZGEF2 PDZ Domain Containing Guanine Nucleotide Exchange Factor (GEF) 2 PDZ Domain-Containing Guanine Nucleotide Exchange Factor 2 Rap Guanine Nucleotide Exchange Factor (GEF) 6 PDZ Domain-Containing Guanine Nucleotide Exchange Factor I KIA001LB RAGEF2
Location (GRCh37)
5:130759766-130970853 UCSC Genome Browser
Location (GRCh38)
Host gene
RAPGEF6
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_RAPGEF6_0022600 Intron-Intron chr5:130888448-130897090 chr5:131552755-131561397 250 nt 0.2920
hsa_chr5_0113800 Intergenic-Intergenic chr5:130894722-130894957 chr5:131559029-131559264 236 nt 0.5127
hsa_chr5_0113900 Intergenic-Intergenic chr5:130894722-130895278 chr5:131559029-131559585 557 nt 0.4291
hsa_RAPGEF6_0022700 Intron-Intron chr5:130905708-130906719 chr5:131570015-131571026 1012 nt 0.3231
hsa_RAPGEF6_0022800 Intron-Intron chr5:130906120-130907917 chr5:131570427-131572224 1798 nt 0.3882
hsa_RAPGEF6_0022900 Intron-Exon-Intron chr5:130906120-130938903 chr5:131570427-131603210 150 nt 0.4000
hsa_RAPGEF6_0023000 Intron-Exon-Intron chr5:130906120-130940386 chr5:131570427-131604693 175 nt 0.4286
hsa_RAPGEF6_0023100 Intron-Intron chr5:130913708-130913938 chr5:131578015-131578245 231 nt 0.4372
hsa_RAPGEF6_0023200 Intron-Intron chr5:130919263-130919404 chr5:131583570-131583711 139 nt 0.4101
hsa_chr5_0114000 Intergenic-Intergenic chr5:130924372-130927645 chr5:131588679-131591952 250 nt 0.3800
Showing 231 to 240 of 253 entries
Forensic Context

A study in mice demonstrated that the circRAPGEF6 was differentially expressed in methamphetamine-treated primary cortical neurons, with RNA sequencing indicating up-regulation, though qRT-PCR validation showed an opposite expression pattern [Li et al. DOI:10.1016/J.Neulet.2019.02.032].