Basic Information
Symbol
circRASA3
RNA Class
circRNA
Alias
RAS P21 Protein Activator 3
GAP1IP4BP
GAPIII
Ras GTPase-Activating Protein 3
Ins P4-Binding Protein
GTPase-Activating Protein 1 Family, Inositol 1,3,4,5-Tetrakisphosphate-Binding Protein
Ins(1,3,4,5)P4-Binding Protein
GTPase Activating Protein III
GAP1(IP4BP)
Location (GRCh37)
13:114806476-114817630
UCSC Genome Browser
Location (GRCh38)
13:114041000-114052155
Host gene
RASA3
Host category
mRNA
Forensic tag(s)
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_RASA3_0005300 | Exon-Exon | chr13:114806476-114817630 | chr13:114041000-114052155 | 199 nt | 0.5176 |
Forensic Context
A study in humans demonstrated that circRASA3 is significantly upregulated in peripheral blood mononuclear cells of tuberculosis patients, where its expression correlates with disease severity and declines following treatment [Lee et al. DOI:10.1016/j.biopha.2018.12.052]. A study in human neonates identified 296 differentially expressed circular RNAs in peripheral blood from asphyxia-induced acute kidney injury cases, with the circRASA3 being one of ten selected for initial screening where it was found to be downregulated (Fold Change = -4.26) based on high-throughput sequencing [Pan et al. DOI:10.1002/kjm2.12644].