Basic Information
Symbol
circASPH
RNA Class
circRNA
Alias
Aspartate Beta-Hydroxylase
BAH
CASQ2BP1
JCTN
HAAH
Aspartyl/Asparaginyl Beta-Hydroxylase
Peptide-Aspartate Beta-Dioxygenase
ASP Beta-Hydroxylase
Junctate
Junctin
Humbug
Cardiac Junctin
EC 1.14.11.16
A Beta H-J-J
FDLAB
AAH
Location (GRCh37)
8:62531537-62566219
UCSC Genome Browser
Location (GRCh38)
8:61618978-61653660
Host gene
ASPH
Host category
mRNA
Forensic tag(s)
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ASPH_0013200 | Exon-Exon | chr8:62531537-62566219 | chr8:61618978-61653660 | 654 nt | 0.4327 |
Forensic Context
A study in human fibroblasts and murine testis demonstrated that exonic circular RNAs (ecircRNAs) are abundant, stable, conserved, and nonrandom splicing products, with specific examples like HIPK2 and HIPK3 circular RNAs being conserved between these species and validated through RNase R enrichment, stability assays, and cytoplasmic localization [Jeck et al. DOI:10.1261/rna.035667.112]. A subsequent review highlighted that the circASPH and numerous other circRNAs are found in human biofluids like blood and saliva and exhibit differential expression across various human diseases, supporting their investigation as potential clinical biomarkers [Lee et al. DOI:10.1016/j.biopha.2018.12.052].