Basic Information
Symbol
circRPPH1
RNA Class
circRNA
Alias
Ribonuclease P RNA Component H1
RPPH1-1
H1RNA
Lnc-CCNB1IP1-1
HSALNG0099785
H1 RNA
Location (GRCh37)
14:20811405-20811559
UCSC Genome Browser
Location (GRCh38)
14:20343246-20343400
Host gene
RPPH1
Host category
lncRNA
Forensic tag(s)
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_RPPH1_0002600 | Exon-Exon | chr14:20811405-20811554 | chr14:20343246-20343395 | 150 nt | 0.6467 |
| hsa_RPPH1_0003100 | Exon-Exon | chr14:20811437-20811559 | chr14:20343278-20343400 | 123 nt | 0.6341 |
Forensic Context
A review of hypoxia-induced circular RNAs in human diseases, including studies in human and mouse models, identified numerous circRNAs with roles in cancer progression, therapeutic resistance, angiogenesis, and energy metabolism [Huang et al. DOI:10.3390/cells11091381]. A study in humans demonstrated that the circRPPH1 was validated as a circular RNA resistant to RNase R and detectable via RT-qPCR and agarose gel electrophoresis, confirming its expression even when its host gene showed no linear RNA expression [Li et al. DOI:10.1093/bib/bby006].