Basic Information
Symbol
circASTN1
RNA Class
circRNA
Alias
Astrotactin 1
ASTN
Astrotactin-1
Astrotactin
KIAA0289
Location (GRCh37)
1:176826120-177101054
UCSC Genome Browser
Location (GRCh38)
1:176856984-177131918
Host gene
ASTN1
Host category
mRNA
Forensic tag(s)
Wound age identification
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ASTN1_0007800 | Exon-Intron | chr1:176992540-177100979 | chr1:177023404-177131843 | 250 nt | 0.4640 |
| hsa_ASTN1_0008200 | Exon-Exon | chr1:176992666-176998789 | chr1:177023530-177029653 | 212 nt | 0.5708 |
| hsa_ASTN1_0008300 | Exon-Exon | chr1:176998770-177000088 | chr1:177029634-177030952 | 255 nt | 0.5098 |
| hsa_ASTN1_0008400 | Exon-Exon | chr1:176998770-177001985 | chr1:177029634-177032849 | 649 nt | 0.5732 |
| hsa_ASTN1_0008500 | Intron-Intron | chr1:177017030-177017662 | chr1:177047894-177048526 | 633 nt | 0.4581 |
| hsa_ASTN1_0008700 | Intron-Exon-Intron | chr1:177024288-177040819 | chr1:177055152-177071683 | 86 nt | 0.4302 |
| hsa_ASTN1_0009000 | Intron-Exon-Intron | chr1:177030214-177033628 | chr1:177061078-177064492 | 250 nt | 0.4160 |
| hsa_ASTN1_0009400 | Intron-Exon-Intron | chr1:177030214-177040262 | chr1:177061078-177071126 | 188 nt | 0.5319 |
| hsa_ASTN1_0009100 | Intron-Exon-Intron | chr1:177030214-177040271 | chr1:177061078-177071135 | 250 nt | 0.3920 |
| hsa_ASTN1_0009200 | Intron-Exon-Intron | chr1:177030214-177049380 | chr1:177061078-177080244 | 250 nt | 0.3840 |
Showing 91 to 100 of 105 entries
Forensic Context
A study in mice and human-derived cells demonstrated that exosomes from adipose-derived stem cells expressing the circASTN1 promote SIRT1 expression and enhance endothelial progenitor cell function under hyperglycemic conditions, indicating a role in diabetic wound healing [Cheng et al. DOI:10.1093/burnst/tkae043]. In human postmortem brain studies, the linear transcript ASTN1 was identified as a target in a circRNA-miRNA-mRNA interaction network within the nucleus accumbens of subjects with alcohol dependence, where it was positively correlated with circRNA-406742 and negatively correlated with miR-1200 [Vornholt et al. DOI:10.1111/Adb.13071].