Basic Information
Symbol
circASTN1
RNA Class
circRNA
Alias
Astrotactin 1
ASTN
Astrotactin-1
Astrotactin
KIAA0289
Location (GRCh37)
1:176826120-177101054
UCSC Genome Browser
Location (GRCh38)
1:176856984-177131918
Host gene
ASTN1
Host category
mRNA
Forensic tag(s)
Wound age identification
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ASTN1_0003700 | Intron-Exon-Intron | chr1:176900662-176913154 | chr1:176931526-176944018 | 250 nt | 0.3840 |
| hsa_ASTN1_0003800 | Intron-Exon-Intron | chr1:176900662-176915256 | chr1:176931526-176946120 | 250 nt | 0.3960 |
| hsa_ASTN1_0003900 | Intron-Exon-Intron | chr1:176900662-176918487 | chr1:176931526-176949351 | 250 nt | 0.4200 |
| hsa_ASTN1_0004200 | Exon-Exon | chr1:176903288-176918487 | chr1:176934152-176949351 | 784 nt | 0.5510 |
| hsa_ASTN1_0004300 | Exon-Exon | chr1:176903288-176934373 | chr1:176934152-176965237 | 1148 nt | 0.5409 |
| hsa_ASTN1_0005200 | Exon-Exon | chr1:176913027-176934373 | chr1:176943891-176965237 | 854 nt | 0.5445 |
| hsa_ASTN1_0005800 | Exon-Exon | chr1:176926814-176934373 | chr1:176957678-176965237 | 364 nt | 0.5192 |
| hsa_ASTN1_0005900 | Exon-Exon | chr1:176926814-176984011 | chr1:176957678-177014875 | 449 nt | 0.5167 |
| hsa_ASTN1_0007100 | Exon-Exon | chr1:176983927-177001985 | chr1:177014791-177032849 | 1076 nt | 0.5771 |
| hsa_ASTN1_0007200 | Exon-Exon | chr1:176983927-177030401 | chr1:177014791-177061265 | 1264 nt | 0.5704 |
Showing 11 to 20 of 105 entries
Forensic Context
A study in mice and human-derived cells demonstrated that exosomes from adipose-derived stem cells expressing the circASTN1 promote SIRT1 expression and enhance endothelial progenitor cell function under hyperglycemic conditions, indicating a role in diabetic wound healing [Cheng et al. DOI:10.1093/burnst/tkae043]. In human postmortem brain studies, the linear transcript ASTN1 was identified as a target in a circRNA-miRNA-mRNA interaction network within the nucleus accumbens of subjects with alcohol dependence, where it was positively correlated with circRNA-406742 and negatively correlated with miR-1200 [Vornholt et al. DOI:10.1111/Adb.13071].