Basic Information
Symbol
circASTN1
RNA Class
circRNA
Alias
Astrotactin 1
ASTN
Astrotactin-1
Astrotactin
KIAA0289
Location (GRCh37)
1:176826120-177101054
UCSC Genome Browser
Location (GRCh38)
1:176856984-177131918
Host gene
ASTN1
Host category
mRNA
Forensic tag(s)
Wound age identification
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ASTN1_0007700 | Exon-Exon | chr1:176992540-177001985 | chr1:177023404-177032849 | 967 nt | 0.5781 |
| hsa_ASTN1_0008600 | Intron-Exon-Intron | chr1:177024288-177030401 | chr1:177055152-177061265 | 250 nt | 0.3680 |
| hsa_ASTN1_0008800 | Exon-Exon | chr1:177030214-177030401 | chr1:177061078-177061265 | 188 nt | 0.5319 |
| hsa_ASTN1_0008900 | Intron-Exon-Intron | chr1:177030214-177100979 | chr1:177061078-177131843 | 250 nt | 0.4400 |
| hsa_ASTN1_0000100 | Intergenic-Exon | chr1:176826120-176853514 | chr1:176856984-176884378 | 1128 nt | 0.4557 |
| hsa_ASTN1_0000200 | Intergenic-Exon | chr1:176826322-176826486 | chr1:176857186-176857350 | 165 nt | 0.2788 |
| hsa_ASTN1_0000400 | Exon-Exon | chr1:176830600-176830740 | chr1:176861464-176861604 | 141 nt | 0.4539 |
| hsa_ASTN1_0000500 | Exon-Exon | chr1:176831104-176832610 | chr1:176861968-176863474 | 1507 nt | 0.4738 |
| hsa_ASTN1_0000800 | Exon-Exon | chr1:176832491-176838163 | chr1:176863355-176869027 | 1351 nt | 0.4863 |
| hsa_ASTN1_0000900 | Exon-Exon | chr1:176832491-176853626 | chr1:176863355-176884490 | 1740 nt | 0.5006 |
Showing 21 to 30 of 105 entries
Forensic Context
A study in mice and human-derived cells demonstrated that exosomes from adipose-derived stem cells expressing the circASTN1 promote SIRT1 expression and enhance endothelial progenitor cell function under hyperglycemic conditions, indicating a role in diabetic wound healing [Cheng et al. DOI:10.1093/burnst/tkae043]. In human postmortem brain studies, the linear transcript ASTN1 was identified as a target in a circRNA-miRNA-mRNA interaction network within the nucleus accumbens of subjects with alcohol dependence, where it was positively correlated with circRNA-406742 and negatively correlated with miR-1200 [Vornholt et al. DOI:10.1111/Adb.13071].