Basic Information
Symbol
circASTN1
RNA Class
circRNA
Alias
Astrotactin 1
ASTN
Astrotactin-1
Astrotactin
KIAA0289
Location (GRCh37)
1:176826120-177101054
UCSC Genome Browser
Location (GRCh38)
1:176856984-177131918
Host gene
ASTN1
Host category
mRNA
Forensic tag(s)
Wound age identification
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ASTN1_0000600 | Exon-Exon | chr1:176832491-176863966 | chr1:176863355-176894830 | 2143 nt | 0.5170 |
| hsa_ASTN1_0000700 | Exon-Intron | chr1:176832491-176941498 | chr1:176863355-176972362 | 250 nt | 0.3680 |
| hsa_ASTN1_0001400 | Exon-Exon | chr1:176837980-176852130 | chr1:176868844-176882994 | 421 nt | 0.5321 |
| hsa_ASTN1_0001500 | Exon-Exon | chr1:176837980-176853626 | chr1:176868844-176884490 | 285 nt | 0.5474 |
| hsa_ASTN1_0001600 | Exon-Exon | chr1:176837980-176905506 | chr1:176868844-176936370 | 246 nt | 0.5163 |
| hsa_ASTN1_0001700 | Intron-Intron | chr1:176841825-176841964 | chr1:176872689-176872828 | 140 nt | 0.5214 |
| hsa_ASTN1_0001800 | Intron-Intron | chr1:176844774-176844956 | chr1:176875638-176875820 | 183 nt | 0.3497 |
| hsa_ASTN1_0002000 | Intron-Intron | chr1:176845774-176846516 | chr1:176876638-176877380 | 743 nt | 0.4953 |
| hsa_ASTN1_0002300 | Exon-Exon | chr1:176851995-176915256 | chr1:176882859-176946120 | 1308 nt | 0.5505 |
| hsa_ASTN1_0002500 | Exon-Exon | chr1:176851995-176927618 | chr1:176882859-176958482 | 142 nt | 0.4930 |
Showing 31 to 40 of 105 entries
Forensic Context
A study in mice and human-derived cells demonstrated that exosomes from adipose-derived stem cells expressing the circASTN1 promote SIRT1 expression and enhance endothelial progenitor cell function under hyperglycemic conditions, indicating a role in diabetic wound healing [Cheng et al. DOI:10.1093/burnst/tkae043]. In human postmortem brain studies, the linear transcript ASTN1 was identified as a target in a circRNA-miRNA-mRNA interaction network within the nucleus accumbens of subjects with alcohol dependence, where it was positively correlated with circRNA-406742 and negatively correlated with miR-1200 [Vornholt et al. DOI:10.1111/Adb.13071].