Basic Information
Symbol
circASTN1
RNA Class
circRNA
Alias
Astrotactin 1
ASTN
Astrotactin-1
Astrotactin
KIAA0289
Location (GRCh37)
1:176826120-177101054
UCSC Genome Browser
Location (GRCh38)
1:176856984-177131918
Host gene
ASTN1
Host category
mRNA
Forensic tag(s)
Wound age identification
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ASTN1_0002400 | Exon-Exon | chr1:176851995-176934373 | chr1:176882859-176965237 | 1839 nt | 0.5492 |
| hsa_ASTN1_0002600 | Exon-Exon | chr1:176853475-176903476 | chr1:176884339-176934340 | 152 nt | 0.5526 |
| hsa_ASTN1_0002700 | Intron-Intron | chr1:176856554-176856911 | chr1:176887418-176887775 | 358 nt | 0.4078 |
| hsa_ASTN1_0002800 | Exon-Exon | chr1:176857207-177030401 | chr1:176888071-177061265 | 134 nt | 0.5821 |
| hsa_ASTN1_0002900 | Exon-Exon | chr1:176863698-176863966 | chr1:176894562-176894830 | 269 nt | 0.5911 |
| hsa_ASTN1_0003000 | Exon-Exon | chr1:176863698-176934373 | chr1:176894562-176965237 | 1417 nt | 0.5505 |
| hsa_chr1_0345400 | Intergenic-Intergenic | chr1:176867588-176867827 | chr1:176898452-176898691 | 240 nt | 0.4292 |
| hsa_chr1_0345500 | Intergenic-Intergenic | chr1:176867643-176867827 | chr1:176898507-176898691 | 185 nt | 0.4703 |
| hsa_ASTN1_0003100 | Intron-Intron | chr1:176870905-176871250 | chr1:176901769-176902114 | 346 nt | 0.3960 |
| hsa_chr1_0345600 | Intergenic-Intergenic | chr1:176876241-176939170 | chr1:176907105-176970034 | 250 nt | 0.3800 |
Showing 41 to 50 of 105 entries
Forensic Context
A study in mice and human-derived cells demonstrated that exosomes from adipose-derived stem cells expressing the circASTN1 promote SIRT1 expression and enhance endothelial progenitor cell function under hyperglycemic conditions, indicating a role in diabetic wound healing [Cheng et al. DOI:10.1093/burnst/tkae043]. In human postmortem brain studies, the linear transcript ASTN1 was identified as a target in a circRNA-miRNA-mRNA interaction network within the nucleus accumbens of subjects with alcohol dependence, where it was positively correlated with circRNA-406742 and negatively correlated with miR-1200 [Vornholt et al. DOI:10.1111/Adb.13071].