Basic Information
Symbol
circASTN1
RNA Class
circRNA
Alias
Astrotactin 1
ASTN
Astrotactin-1
Astrotactin
KIAA0289
Location (GRCh37)
1:176826120-177101054
UCSC Genome Browser
Location (GRCh38)
1:176856984-177131918
Host gene
ASTN1
Host category
mRNA
Forensic tag(s)
Wound age identification
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ASTN1_0003200 | Intron-Exon-Intron | chr1:176882366-176918487 | chr1:176913230-176949351 | 250 nt | 0.3920 |
| hsa_ASTN1_0004000 | Intron-Exon-Intron | chr1:176900662-176927618 | chr1:176931526-176958482 | 138 nt | 0.5362 |
| hsa_ASTN1_0004100 | Intron-Exon-Intron | chr1:176900662-176934373 | chr1:176931526-176965237 | 159 nt | 0.4088 |
| hsa_ASTN1_0003300 | Intron-Exon-Intron | chr1:176900662-176984011 | chr1:176931526-177014875 | 250 nt | 0.3800 |
| hsa_ASTN1_0003400 | Intron-Exon | chr1:176900662-176999976 | chr1:176931526-177030840 | 250 nt | 0.3920 |
| hsa_ASTN1_0003500 | Intron-Exon-Intron | chr1:176900662-177030401 | chr1:176931526-177061265 | 250 nt | 0.3760 |
| hsa_ASTN1_0004500 | Intron-Exon-Intron | chr1:176903288-176904015 | chr1:176934152-176934879 | 728 nt | 0.4245 |
| hsa_ASTN1_0004800 | Exon-Exon | chr1:176903288-176915256 | chr1:176934152-176946120 | 195 nt | 0.5333 |
| hsa_ASTN1_0004600 | Exon-Exon | chr1:176903288-176927618 | chr1:176934152-176958482 | 1073 nt | 0.5471 |
| hsa_ASTN1_0004900 | Intron-Exon-Intron | chr1:176903288-176946654 | chr1:176934152-176977518 | 327 nt | 0.5138 |
Showing 51 to 60 of 105 entries
Forensic Context
A study in mice and human-derived cells demonstrated that exosomes from adipose-derived stem cells expressing the circASTN1 promote SIRT1 expression and enhance endothelial progenitor cell function under hyperglycemic conditions, indicating a role in diabetic wound healing [Cheng et al. DOI:10.1093/burnst/tkae043]. In human postmortem brain studies, the linear transcript ASTN1 was identified as a target in a circRNA-miRNA-mRNA interaction network within the nucleus accumbens of subjects with alcohol dependence, where it was positively correlated with circRNA-406742 and negatively correlated with miR-1200 [Vornholt et al. DOI:10.1111/Adb.13071].