Basic Information
Symbol
circASTN1
RNA Class
circRNA
Alias
Astrotactin 1
ASTN
Astrotactin-1
Astrotactin
KIAA0289
Location (GRCh37)
1:176826120-177101054
UCSC Genome Browser
Location (GRCh38)
1:176856984-177131918
Host gene
ASTN1
Host category
mRNA
Forensic tag(s)
Wound age identification
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ASTN1_0004700 | Exon-Exon | chr1:176903288-176984011 | chr1:176934152-177014875 | 1233 nt | 0.5385 |
| hsa_ASTN1_0004400 | Intron-Exon-Intron | chr1:176903288-177033628 | chr1:176934152-177064492 | 250 nt | 0.3960 |
| hsa_ASTN1_0005000 | Exon-Exon | chr1:176905402-176934373 | chr1:176936266-176965237 | 959 nt | 0.5433 |
| hsa_ASTN1_0005100 | Intron-Intron | chr1:176906272-176906663 | chr1:176937136-176937527 | 392 nt | 0.3827 |
| hsa_ASTN1_0005300 | Exon-Exon | chr1:176913027-176918487 | chr1:176943891-176949351 | 490 nt | 0.5633 |
| hsa_ASTN1_0005500 | Exon-Exon | chr1:176915062-176927618 | chr1:176945926-176958482 | 651 nt | 0.5530 |
| hsa_ASTN1_0005400 | Intron-Exon-Intron | chr1:176915062-176979943 | chr1:176945926-177010807 | 250 nt | 0.3760 |
| hsa_ASTN1_0005600 | Intron-Intron | chr1:176923138-176923303 | chr1:176954002-176954167 | 166 nt | 0.5120 |
| hsa_ASTN1_0005700 | Intron-Intron | chr1:176924888-176925316 | chr1:176955752-176956180 | 429 nt | 0.4732 |
| hsa_ASTN1_0006000 | Intron-Exon-Intron | chr1:176926814-176946654 | chr1:176957678-176977518 | 63 nt | 0.5397 |
Showing 61 to 70 of 105 entries
Forensic Context
A study in mice and human-derived cells demonstrated that exosomes from adipose-derived stem cells expressing the circASTN1 promote SIRT1 expression and enhance endothelial progenitor cell function under hyperglycemic conditions, indicating a role in diabetic wound healing [Cheng et al. DOI:10.1093/burnst/tkae043]. In human postmortem brain studies, the linear transcript ASTN1 was identified as a target in a circRNA-miRNA-mRNA interaction network within the nucleus accumbens of subjects with alcohol dependence, where it was positively correlated with circRNA-406742 and negatively correlated with miR-1200 [Vornholt et al. DOI:10.1111/Adb.13071].