Basic Information
Symbol
circASTN1
RNA Class
circRNA
Alias
Astrotactin 1
ASTN
Astrotactin-1
Astrotactin
KIAA0289
Location (GRCh37)
1:176826120-177101054
UCSC Genome Browser
Location (GRCh38)
1:176856984-177131918
Host gene
ASTN1
Host category
mRNA
Forensic tag(s)
Wound age identification
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ASTN1_0006100 | Exon-Exon | chr1:176926814-177030401 | chr1:176957678-177061265 | 151 nt | 0.5364 |
| hsa_ASTN1_0006200 | Exon-Exon | chr1:176926925-176927497 | chr1:176957789-176958361 | 46 nt | 0.5435 |
| hsa_ASTN1_0006300 | Intron-Exon-Intron | chr1:176927415-176928188 | chr1:176958279-176959052 | 774 nt | 0.4897 |
| hsa_ASTN1_0006400 | Exon-Exon | chr1:176934299-176993868 | chr1:176965163-177024732 | 502 nt | 0.5637 |
| hsa_ASTN1_0006500 | Exon-Exon | chr1:176934299-176998877 | chr1:176965163-177029741 | 610 nt | 0.5623 |
| hsa_ASTN1_0006600 | Exon-Exon | chr1:176934299-177000088 | chr1:176965163-177030952 | 222 nt | 0.4685 |
| hsa_ASTN1_0006700 | Intron-Intron | chr1:176942440-176942884 | chr1:176973304-176973748 | 445 nt | 0.4270 |
| hsa_chr1_0345800 | Intergenic-Intergenic | chr1:176957093-176957358 | chr1:176987957-176988222 | 266 nt | 0.3910 |
| hsa_chr1_0345900 | Intergenic-Intergenic | chr1:176957151-176957358 | chr1:176988015-176988222 | 208 nt | 0.3990 |
| hsa_ASTN1_0006800 | Intron-Exon-Intron | chr1:176971955-176984011 | chr1:177002819-177014875 | 250 nt | 0.3400 |
Showing 71 to 80 of 105 entries
Forensic Context
A study in mice and human-derived cells demonstrated that exosomes from adipose-derived stem cells expressing the circASTN1 promote SIRT1 expression and enhance endothelial progenitor cell function under hyperglycemic conditions, indicating a role in diabetic wound healing [Cheng et al. DOI:10.1093/burnst/tkae043]. In human postmortem brain studies, the linear transcript ASTN1 was identified as a target in a circRNA-miRNA-mRNA interaction network within the nucleus accumbens of subjects with alcohol dependence, where it was positively correlated with circRNA-406742 and negatively correlated with miR-1200 [Vornholt et al. DOI:10.1111/Adb.13071].