Basic Information
Symbol
circASTN1
RNA Class
circRNA
Alias
Astrotactin 1
ASTN
Astrotactin-1
Astrotactin
KIAA0289
Location (GRCh37)
1:176826120-177101054
UCSC Genome Browser
Location (GRCh38)
1:176856984-177131918
Host gene
ASTN1
Host category
mRNA
Forensic tag(s)
Wound age identification
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ASTN1_0006900 | Intron-Exon-Intron | chr1:176971955-176986867 | chr1:177002819-177017731 | 250 nt | 0.3640 |
| hsa_ASTN1_0007000 | Intron-Intron | chr1:176980304-176980445 | chr1:177011168-177011309 | 142 nt | 0.3803 |
| hsa_ASTN1_0007300 | Exon-Exon | chr1:176983927-176993868 | chr1:177014791-177024732 | 403 nt | 0.5707 |
| hsa_ASTN1_0007400 | Exon-Exon | chr1:176983927-177000088 | chr1:177014791-177030952 | 85 nt | 0.5059 |
| hsa_chr1_0346000 | Intergenic-Intergenic | chr1:176983962-177001644 | chr1:177014826-177032508 | 50 nt | 0.4800 |
| hsa_ASTN1_0007500 | Exon-Exon | chr1:176992516-176993868 | chr1:177023380-177024732 | 342 nt | 0.6023 |
| hsa_ASTN1_0007600 | Exon-Exon | chr1:176992516-177001985 | chr1:177023380-177032849 | 991 nt | 0.5832 |
| hsa_ASTN1_0007900 | Exon-Exon | chr1:176992540-176993819 | chr1:177023404-177024683 | 269 nt | 0.5985 |
| hsa_ASTN1_0008000 | Exon-Exon | chr1:176992540-176993868 | chr1:177023404-177024732 | 318 nt | 0.5881 |
| hsa_ASTN1_0008100 | Exon-Exon | chr1:176992540-177030401 | chr1:177023404-177061265 | 1155 nt | 0.5706 |
Showing 81 to 90 of 105 entries
Forensic Context
A study in mice and human-derived cells demonstrated that exosomes from adipose-derived stem cells expressing the circASTN1 promote SIRT1 expression and enhance endothelial progenitor cell function under hyperglycemic conditions, indicating a role in diabetic wound healing [Cheng et al. DOI:10.1093/burnst/tkae043]. In human postmortem brain studies, the linear transcript ASTN1 was identified as a target in a circRNA-miRNA-mRNA interaction network within the nucleus accumbens of subjects with alcohol dependence, where it was positively correlated with circRNA-406742 and negatively correlated with miR-1200 [Vornholt et al. DOI:10.1111/Adb.13071].