Forensic RNA Knowledge Base

Basic Information

Symbol

circSERPINB3

RNA Class

circRNA

Alias

Serpin Family B Member 3 Squamous Cell Carcinoma Antigen 1 HsT1196 SCCA1 T4-A Serine (Or Cysteine) Proteinase Inhibitor, Clade B (Ovalbumin), Member 3 Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 Protein T4-A Serpin B3 SCCA-1 SCC SCCA-PD SSCA1 SCCA

Location (GRCh37)

18:61324504-61328476 UCSC Genome Browser

Location (GRCh38)

18:63657270-63661242

UCSC Genome Browser Search in Marker Scope

Host gene

SERPINB3

Host category

mRNA

Forensic tag(s)

Tissue/body fluid identification

External database

circbank

Transcripts

ID	Type	Location (GRCh37)	Location (GRCh38)	Length	GC content
hsa_SERPINB3_0000200	Exon-Exon	chr18:61324504-61328476	chr18:63657270-63661242	248 nt	0.4234

Forensic Context

A study in humans demonstrated that the circSERPINB3 is expressed as both mRNA and circular RNA (circRNA) in vaginal secretions and can be used as a biomarker for this body fluid [Liu et al. DOI:10.1007/s00414-019-02027-y]. A review confirms the circSERPINB3 circRNA is among the markers used for the RNA-based identification of vaginal secretions in forensic molecular biology [Courts et al. DOI:10.3238/arztebl.m2024.0051].