Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0004400 Exon-Exon chr6:146209156-146216113 chr6:145888020-145894977 440 nt 0.4205
hsa_SHPRH_0000400 Intergenic-Exon chr6:146125508-146209236 chr6:145804372-145888100 250 nt 0.3280
hsa_SHPRH_0001600 Exon-Intergenic chr6:146185524-146216108 chr6:145864388-145894972 250 nt 0.3600
hsa_SHPRH_0001700 Exon-Intergenic chr6:146185524-146216113 chr6:145864388-145894977 250 nt 0.3720
hsa_SHPRH_0002800 Intergenic-Exon chr6:146202764-146216113 chr6:145881628-145894977 250 nt 0.3560
hsa_SHPRH_0003000 Intergenic-Exon chr6:146205045-146216113 chr6:145883909-145894977 250 nt 0.3360
hsa_SHPRH_0004200 Exon-Exon chr6:146209156-146214529 chr6:145888020-145893393 260 nt 0.4308
hsa_SHPRH_0004300 Exon-Exon chr6:146209156-146216108 chr6:145888020-145894972 435 nt 0.4161
hsa_SHPRH_0004400 Exon-Exon chr6:146209156-146216113 chr6:145888020-145894977 440 nt 0.4205
hsa_SHPRH_0004500 Exon-Exon chr6:146209156-146240627 chr6:145888020-145919491 947 nt 0.4277
Showing 1 to 10 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].