Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0007500 Exon-Exon chr6:146231584-146276490 chr6:145910448-145955354 250 nt 0.3840
hsa_SHPRH_0008200 Exon-Exon chr6:146234614-146243484 chr6:145913478-145922348 135 nt 0.4074
hsa_SHPRH_0008100 Exon-Exon chr6:146234614-146264938 chr6:145913478-145943802 2760 nt 0.4355
hsa_SHPRH_0008300 Exon-Exon chr6:146239267-146242528 chr6:145918131-145921392 328 nt 0.3994
hsa_SHPRH_0008400 Exon-Exon chr6:146239267-146243484 chr6:145918131-145922348 63 nt 0.3492
hsa_SHPRH_0008500 Exon-Exon chr6:146239267-146248413 chr6:145918131-145927277 102 nt 0.3529
hsa_SHPRH_0008600 Exon-Exon chr6:146239267-146264938 chr6:145918131-145943802 108 nt 0.3611
hsa_SHPRH_0008700 Intron-Intron chr6:146239369-146240483 chr6:145918233-145919347 1115 nt 0.3085
hsa_SHPRH_0008900 Exon-Exon chr6:146239675-146240483 chr6:145918539-145919347 194 nt 0.4278
hsa_SHPRH_0008800 Intron-Exon-Intron chr6:146239675-146266773 chr6:145918539-145945637 250 nt 0.3160
Showing 91 to 100 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].