Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0009000 Intron-Exon chr6:146240386-146254314 chr6:145919250-145933178 128 nt 0.4141
hsa_SHPRH_0009300 Exon-Exon chr6:146240484-146242460 chr6:145919348-145921324 302 nt 0.4338
hsa_SHPRH_0009400 Exon-Exon chr6:146240484-146248413 chr6:145919348-145927277 144 nt 0.4583
hsa_SHPRH_0009500 Exon-Exon chr6:146240484-146254331 chr6:145919348-145933195 283 nt 0.4311
hsa_SHPRH_0009600 Exon-Exon chr6:146240484-146263010 chr6:145919348-145941874 1920 nt 0.4495
hsa_SHPRH_0009700 Exon-Exon chr6:146240484-146276490 chr6:145919348-145955354 207 nt 0.4251
hsa_chr6_0217700 Intergenic-Intergenic chr6:146240588-146242457 chr6:145919452-145921321 195 nt 0.4103
hsa_SHPRH_0009800 Exon-Exon chr6:146242303-146243972 chr6:145921167-145922836 463 nt 0.4233
hsa_SHPRH_0009900 Exon-Exon chr6:146242428-146244921 chr6:145921292-145923785 244 nt 0.4344
hsa_SHPRH_0010100 Exon-Exon chr6:146243422-146256577 chr6:145922286-145935441 63 nt 0.3492
Showing 101 to 110 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].