Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0010000 Intron-Exon-Intron chr6:146243422-146273059 chr6:145922286-145951923 250 nt 0.3760
hsa_SHPRH_0010400 Exon-Exon chr6:146243799-146247432 chr6:145922663-145926296 375 nt 0.4720
hsa_SHPRH_0010500 Exon-Exon chr6:146243799-146248413 chr6:145922663-145927277 263 nt 0.4525
hsa_SHPRH_0010600 Exon-Exon chr6:146243799-146254314 chr6:145922663-145933178 528 nt 0.4280
hsa_SHPRH_0010700 Exon-Exon chr6:146243799-146263010 chr6:145922663-145941874 1487 nt 0.4573
hsa_SHPRH_0010300 Exon-Exon chr6:146243799-146264938 chr6:145922663-145943802 2153 nt 0.4412
hsa_SHPRH_0010900 Exon-Exon chr6:146244779-146254314 chr6:145923643-145933178 143 nt 0.3916
hsa_SHPRH_0010800 Exon-Exon chr6:146244779-146271618 chr6:145923643-145950482 2809 nt 0.4336
hsa_SHPRH_0011000 Exon-Exon chr6:146245875-146256299 chr6:145924739-145935163 192 nt 0.4635
hsa_SHPRH_0011100 Intron-Intron chr6:146246315-146246639 chr6:145925179-145925503 325 nt 0.3077
Showing 111 to 120 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].