Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0011200 Exon-Exon chr6:146247340-146254314 chr6:145926204-145933178 129 nt 0.4186
hsa_SHPRH_0011300 Exon-Exon chr6:146247340-146256299 chr6:145926204-145935163 379 nt 0.4749
hsa_SHPRH_0011400 Exon-Exon chr6:146248325-146276092 chr6:145927189-145954956 2862 nt 0.4207
hsa_chr6_0217800 Intergenic-Intergenic chr6:146253362-146253654 chr6:145932226-145932518 293 nt 0.3345
hsa_SHPRH_0011600 Exon-Exon chr6:146254193-146271618 chr6:145933057-145950482 201 nt 0.4229
hsa_SHPRH_0011500 Exon-Exon chr6:146254193-146275989 chr6:145933057-145954853 2670 nt 0.4228
hsa_SHPRH_0011700 Exon-Exon chr6:146254193-146276077 chr6:145933057-145954941 192 nt 0.3594
hsa_SHPRH_0012300 Exon-Exon chr6:146256216-146256577 chr6:145935080-145935441 164 nt 0.4268
hsa_SHPRH_0012100 Exon-Exon chr6:146256216-146271584 chr6:145935080-145950448 2020 nt 0.4248
hsa_SHPRH_0012200 Exon-Exon chr6:146256216-146275989 chr6:145935080-145954853 2348 nt 0.4170
Showing 121 to 130 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].