Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0013300 Exon-Exon chr6:146264722-146266549 chr6:145943586-145945413 33 nt 0.3030
hsa_SHPRH_0013400 Intron-Exon chr6:146266486-146268703 chr6:145945350-145947567 472 nt 0.3708
hsa_SHPRH_0013600 Exon-Exon chr6:146266517-146273614 chr6:145945381-145952478 1078 nt 0.4156
hsa_SHPRH_0013700 Exon-Exon chr6:146267369-146275989 chr6:145946233-145954853 985 nt 0.4223
hsa_SHPRH_0013800 Exon-Exon chr6:146268629-146271618 chr6:145947493-145950482 151 nt 0.4768
hsa_SHPRH_0013900 Intron-Exon-Intron chr6:146268629-146273059 chr6:145947493-145951923 582 nt 0.4725
hsa_SHPRH_0014000 Exon-Exon chr6:146268629-146273614 chr6:145947493-145952478 712 nt 0.4480
hsa_SHPRH_0014100 Exon-Exon chr6:146271400-146275989 chr6:145950264-145954853 164 nt 0.3720
hsa_SHPRH_0014200 Exon-Exon chr6:146271400-146276490 chr6:145950264-145955354 219 nt 0.4749
hsa_SHPRH_0014300 Exon-Exon chr6:146273485-146276490 chr6:145952349-145955354 130 nt 0.3385
Showing 141 to 150 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].