Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0009200 Exon-Exon chr6:146240484-146285233 chr6:145919348-145964097 250 nt 0.4560
hsa_SHPRH_0010200 Exon-Exon chr6:146243799-146245982 chr6:145922663-145924846 425 nt 0.4376
hsa_SHPRH_0011800 Exon-Exon chr6:146256043-146256299 chr6:145934907-145935163 257 nt 0.5019
hsa_SHPRH_0011900 Exon-Exon chr6:146256043-146256577 chr6:145934907-145935441 421 nt 0.4727
hsa_SHPRH_0012000 Exon-Exon chr6:146256043-146271526 chr6:145934907-145950390 2135 nt 0.4323
hsa_SHPRH_0013500 Exon-Exon chr6:146266517-146276490 chr6:145945381-145955354 1610 nt 0.3981
hsa_SHPRH_0014500 Exon-Exon chr6:146275990-146276322 chr6:145954854-145955186 333 nt 0.3483
hsa_FBXO30_0000800 Exon-Intergenic chr6:146125508-146216113 chr6:145804372-145894977 180 nt 0.4056
hsa_FBXO30_0000900 Exon-Intergenic chr6:146125508-146239770 chr6:145804372-145918634 270 nt 0.4074
hsa_SHPRH_0000100 Intergenic-Exon chr6:146106726-146216113 chr6:145785590-145894977 94 nt 0.4043
Showing 21 to 30 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].