Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0000200 Intergenic-Exon chr6:146121313-146216113 chr6:145800177-145894977 250 nt 0.3640
hsa_SHPRH_0000500 Intergenic-Exon chr6:146142754-146216113 chr6:145821618-145894977 93 nt 0.4731
hsa_SHPRH_0000600 Intergenic-Exon chr6:146179321-146216113 chr6:145858185-145894977 250 nt 0.3240
hsa_SHPRH_0000700 Intergenic-Exon chr6:146179578-146216113 chr6:145858442-145894977 186 nt 0.3978
hsa_SHPRH_0000800 Intergenic-Exon chr6:146179593-146216113 chr6:145858457-145894977 93 nt 0.4731
hsa_SHPRH_0001300 Exon-Exon chr6:146185524-146209236 chr6:145864388-145888100 185 nt 0.4054
hsa_SHPRH_0001400 Exon-Intergenic chr6:146185524-146214529 chr6:145864388-145893393 185 nt 0.4054
hsa_SHPRH_0001500 Exon-Intergenic chr6:146185524-146215372 chr6:145864388-145894236 185 nt 0.4054
hsa_SHPRH_0001800 Exon-Intergenic chr6:146185524-146216142 chr6:145864388-145895006 128 nt 0.4219
hsa_SHPRH_0001000 Intergenic-Exon chr6:146185524-146239368 chr6:145864388-145918232 250 nt 0.3200
Showing 31 to 40 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].