Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0001100 Intergenic-Exon chr6:146185524-146242528 chr6:145864388-145921392 250 nt 0.3800
hsa_SHPRH_0001200 Intergenic-Exon chr6:146185524-146276490 chr6:145864388-145955354 250 nt 0.3760
hsa_SHPRH_0001900 Exon-Intergenic chr6:146185531-146216108 chr6:145864395-145894972 185 nt 0.4541
hsa_SHPRH_0002000 Exon-Intergenic chr6:146185531-146216113 chr6:145864395-145894977 99 nt 0.4646
hsa_SHPRH_0002100 Intergenic-Exon chr6:146198083-146216113 chr6:145876947-145894977 93 nt 0.4731
hsa_SHPRH_0002500 Intergenic-Exon chr6:146201656-146215372 chr6:145880520-145894236 87 nt 0.3333
hsa_SHPRH_0002200 Intergenic-Exon chr6:146201656-146216108 chr6:145880520-145894972 250 nt 0.3960
hsa_SHPRH_0002600 Intergenic-Exon chr6:146201656-146216113 chr6:145880520-145894977 99 nt 0.4848
hsa_SHPRH_0002300 Intergenic-Exon chr6:146201656-146276490 chr6:145880520-145955354 250 nt 0.4120
hsa_SHPRH_0002700 Intergenic-Exon chr6:146202451-146216113 chr6:145881315-145894977 250 nt 0.4000
Showing 41 to 50 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].