Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0002900 Intergenic-Exon chr6:146202764-146216108 chr6:145881628-145894972 544 nt 0.4136
hsa_SHPRH_0003100 Intergenic-Exon chr6:146205045-146214529 chr6:145883909-145893393 81 nt 0.3580
hsa_SHPRH_0003200 Intergenic-Exon chr6:146205045-146216108 chr6:145883909-145894972 175 nt 0.3943
hsa_SHPRH_0003400 Exon-Exon chr6:146207542-146214529 chr6:145886406-145893393 642 nt 0.3769
hsa_SHPRH_0003500 Exon-Exon chr6:146207542-146215372 chr6:145886406-145894236 203 nt 0.3448
hsa_SHPRH_0003600 Exon-Exon chr6:146207542-146216108 chr6:145886406-145894972 88 nt 0.4545
hsa_SHPRH_0003700 Exon-Exon chr6:146207542-146216113 chr6:145886406-145894977 99 nt 0.4747
hsa_SHPRH_0003800 Exon-Exon chr6:146207542-146231618 chr6:145886406-145910482 35 nt 0.5143
hsa_SHPRH_0003900 Exon-Exon chr6:146207542-146247432 chr6:145886406-145926296 93 nt 0.5054
hsa_SHPRH_0004000 Intron-Intron chr6:146207925-146209155 chr6:145886789-145888019 1231 nt 0.3566
Showing 51 to 60 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].