Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0004100 Intron-Exon chr6:146209152-146239364 chr6:145888016-145918228 183 nt 0.3552
hsa_SHPRH_0005400 Exon-Exon chr6:146209156-146215372 chr6:145888020-145894236 87 nt 0.3678
hsa_SHPRH_0005500 Intron-Exon-Intron chr6:146209156-146216142 chr6:145888020-145895006 122 nt 0.4344
hsa_SHPRH_0005600 Exon-Exon chr6:146209156-146234685 chr6:145888020-145913549 512 nt 0.4258
hsa_SHPRH_0005100 Intron-Exon-Intron chr6:146209156-146239770 chr6:145888020-145918634 1205 nt 0.3751
hsa_SHPRH_0005200 Exon-Exon chr6:146209156-146242528 chr6:145888020-145921392 1173 nt 0.4263
hsa_SHPRH_0005700 Exon-Exon chr6:146209156-146243484 chr6:145888020-145922348 63 nt 0.3492
hsa_SHPRH_0005800 Exon-Exon chr6:146209156-146243972 chr6:145888020-145922836 81 nt 0.3580
hsa_SHPRH_0005900 Exon-Exon chr6:146209156-146248413 chr6:145888020-145927277 182 nt 0.4780
hsa_SHPRH_0005300 Exon-Exon chr6:146209156-146254314 chr6:145888020-145933178 1965 nt 0.4305
Showing 61 to 70 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].