Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0006000 Exon-Exon chr6:146209156-146264938 chr6:145888020-145943802 256 nt 0.3828
hsa_SHPRH_0004900 Exon-Exon chr6:146209156-146271618 chr6:145888020-145950482 250 nt 0.3280
hsa_SHPRH_0005000 Exon-Exon chr6:146209156-146273614 chr6:145888020-145952478 250 nt 0.2880
hsa_SHPRH_0006100 Exon-Exon chr6:146209156-146275989 chr6:145888020-145954853 81 nt 0.3580
hsa_chr6_0217300 Intergenic-Intergenic chr6:146209526-146209716 chr6:145888390-145888580 191 nt 0.4974
hsa_chr6_0217400 Intergenic-Intergenic chr6:146209538-146210501 chr6:145888402-145889365 964 nt 0.4523
hsa_chr6_0217500 Intergenic-Intergenic chr6:146213801-146214031 chr6:145892665-145892895 231 nt 0.3550
hsa_SHPRH_0006600 Exon-Exon chr6:146214351-146215372 chr6:145893215-145894236 87 nt 0.3333
hsa_SHPRH_0006400 Exon-Exon chr6:146214351-146240627 chr6:145893215-145919491 866 nt 0.4342
hsa_SHPRH_0006500 Exon-Exon chr6:146214351-146243484 chr6:145893215-145922348 1155 nt 0.4268
Showing 71 to 80 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].