Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0007000 Intron-Exon-Intron chr6:146215286-146215432 chr6:145894150-145894296 147 nt 0.3197
hsa_SHPRH_0006900 Exon-Exon chr6:146215286-146256577 chr6:145894150-145935441 2138 nt 0.4364
hsa_SHPRH_0007200 Intron-Intron chr6:146219431-146219677 chr6:145898295-145898541 247 nt 0.3158
hsa_SHPRH_0007300 Intron-Exon-Intron chr6:146231552-146248413 chr6:145910416-145927277 1435 nt 0.4341
hsa_SHPRH_0007600 Exon-Exon chr6:146231584-146234685 chr6:145910448-145913549 261 nt 0.4521
hsa_SHPRH_0007700 Exon-Exon chr6:146231584-146242349 chr6:145910448-145921213 47 nt 0.3830
hsa_SHPRH_0007800 Exon-Exon chr6:146231584-146244880 chr6:145910448-145923744 1072 nt 0.4254
hsa_SHPRH_0007900 Exon-Exon chr6:146231584-146248413 chr6:145910448-145927277 89 nt 0.4494
hsa_SHPRH_0008000 Exon-Exon chr6:146231584-146256577 chr6:145910448-145935441 164 nt 0.4268
hsa_SHPRH_0007400 Exon-Exon chr6:146231584-146263010 chr6:145910448-145941874 2289 nt 0.4426
Showing 81 to 90 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].