Basic Information
Symbol
circATG4C
RNA Class
circRNA
Alias
Autophagy Related 4C Cysteine Peptidase
AUTL3
APG4C
AUTL1
Autophagy-Related Cysteine Endopeptidase 3
Autophagy-Related Protein 4 Homolog C
AUT-Like 3 Cysteine Endopeptidase
Cysteine Protease ATG4C
Autophagin-3
FLJ14867
HsAPG4C
AUT (S. Cerevisiae)-Like 1, Cysteine Endopeptidase; AUT-Like 1, Cysteine Endopeptidase (S. Cerevisiae)
ATG4 Autophagy Related 4 Homolog C (S. Cerevisiae)
APG4 Autophagy 4 Homolog C (S. Cerevisiae)
Epididymis Secretory Sperm Binding Protein
Autophagy Related 4C, Cysteine Peptidase
ATG4 Autophagy Related 4 Homolog C
AUT-Like 1, Cysteine Endopeptidase
APG4 Autophagy 4 Homolog C
EC 3.4.22.-
EC 3.4.22
APG4-C
Location (GRCh37)
1:63246097-63270926
UCSC Genome Browser
Location (GRCh38)
1:62780426-62805255
Host gene
ATG4C
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ATG4C_0000200 | Intergenic-Exon | chr1:63246097-63270926 | chr1:62780426-62805255 | 250 nt | 0.2520 |
Forensic Context
A study in humans demonstrated that circATG4C is significantly decreased in the peripheral blood of Alzheimer's disease patients and may be used to distinguish them from other dementia cases [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in humans demonstrated that the circATG4C is upregulated in the peripheral blood of coronary artery disease patients, with an area under the curve of 0.689 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].