Basic Information

Symbol
circSLC8A1
RNA Class
circRNA
Alias
Solute Carrier Family 8 Member A1 NCX1 Solute Carrier Family 8 (Sodium/Calcium Exchanger), Member 1 Solute Carrier Family 8 Member 1 Na(+)/Ca(2+)-Exchange Protein 1 Sodium/Calcium Exchanger 1 Na+/Ca++ Exchanger Na+/Ca2+ Exchanger CNC
Location (GRCh37)
2:40325863-40809199 UCSC Genome Browser
Location (GRCh38)
2:40098723-40582059
UCSC Genome Browser Search in Marker Scope
Host gene
SLC8A1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SLC8A1_0025500 Exon-Exon chr2:40656539-40656717 chr2:40429399-40429577 179 nt 0.4358
hsa_SLC8A1_0027600 Intron-Intron chr2:40762099-40787973 chr2:40534959-40560833 250 nt 0.3240
hsa_AC007377.1_0000100 Intergenic-Exon-Intergenic chr2:40486353-40512002 chr2:40259213-40284862 250 nt 0.3480
hsa_AC007377.1_0000100 Intergenic-Exon-Intergenic chr2:40486353-40512002 chr2:40259213-40284862 250 nt 0.3480
hsa_AC007377.1_0000100 Intergenic-Exon-Intergenic chr2:40486353-40512002 chr2:40259213-40284862 250 nt 0.3480
hsa_SLC8A1_0000300 Exon-Exon chr2:40325863-40326058 chr2:40098723-40098918 196 nt 0.2857
hsa_SLC8A1_0000400 Exon-Exon chr2:40338321-40392124 chr2:40111181-40164984 250 nt 0.3520
hsa_SLC8A1_0000600 Exon-Intron chr2:40338321-40397489 chr2:40111181-40170349 300 nt 0.4767
hsa_SLC8A1_0000700 Exon-Exon chr2:40340698-40340944 chr2:40113558-40113804 247 nt 0.4170
hsa_SLC8A1_0000800 Exon-Exon chr2:40341348-40341571 chr2:40114208-40114431 224 nt 0.4554
Showing 71 to 80 of 912 entries
Forensic Context

A study in rats and H9c2 cells demonstrated that the circSLC8A1 is upregulated in ischemic heart disease models [Tian et al. DOI:10.1038/s41598-021-84056-5]. Furthermore, research in human peripheral blood confirmed the circSLC8A1 is significantly upregulated in myocardial infarction patients and exhibits high diagnostic value as a biomarker [Li et al. DOI:10.3389/fcvm.2022.810257]. A study in mice demonstrated that the circSLC8A1 (mmu_circ_004295) is increased with ischemia time in the heart and promotes cardiomyocyte apoptosis by acting as an endogenous miR-133a-3p sponge [Tian et al. DOI:10.3390/molecules26041155].