Basic Information

Symbol
circSMARCA5
RNA Class
circRNA
Alias
SNF2 Related Chromatin Remodeling ATPase 5 HSNF2H HISWI ISWI SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin A5 Sucrose Nonfermenting Protein 2 Homolog WCRF135 SNF2H Sucrose Nonfermenting-Like 5 EC 3.6.4.- EC 3.6.1
Location (GRCh37)
4:144434670-144474749 UCSC Genome Browser
Location (GRCh38)
4:143513517-143553596
UCSC Genome Browser Search in Marker Scope
Host gene
SMARCA5
Host category
mRNA
Forensic tag(s)
Time since deposition estimation Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SMARCA5_0007400 Exon-Exon chr4:144466623-144467200 chr4:143545470-143546047 237 nt 0.3924
hsa_chr4_0157600 Intergenic-Intergenic chr4:144466633-144474299 chr4:143545480-143553146 28 nt 0.4643
hsa_SMARCA5_0007500 Intron-Intron chr4:144466737-144467077 chr4:143545584-143545924 341 nt 0.2903
hsa_SMARCA5_0007600 Exon-Exon chr4:144467078-144468656 chr4:143545925-143547503 375 nt 0.3947
hsa_chr4_0157700 Intergenic-Intergenic chr4:144469100-144471252 chr4:143547947-143550099 194 nt 0.3505
hsa_chr4_0157800 Intergenic-Intergenic chr4:144469100-144474749 chr4:143547947-143553596 780 nt 0.3231
hsa_SMARCA5_0007800 Intron-Intron chr4:144469737-144470931 chr4:143548584-143549778 1195 nt 0.3205
hsa_chr4_0157900 Intergenic-Intergenic chr4:144471201-144474299 chr4:143550048-143553146 85 nt 0.4353
hsa_SMARCA5_0007900 Exon-Exon chr4:144471219-144474305 chr4:143550066-143553152 73 nt 0.4658
hsa_SMARCA5_0008000 Exon-Exon chr4:144471225-144474305 chr4:143550072-143553152 67 nt 0.4627
Showing 91 to 100 of 169 entries
Forensic Context

A study in mice demonstrated that the circSMARCA5 promotes angiogenesis by sponging SRSF1 mRNA to regulate VEGF-A [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in human bloodstains demonstrated that the circSMARCA5 exhibited linear degradation over 120 days, with its relative expression negatively correlated with bloodstain age both indoors (r=0.81) and outdoors (r=0.91), and it was incorporated into a mathematical formula for estimating the time since deposition [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. A separate review noted that in human plasma, the circSMARCA5 is lower in patients with more severe coronary atherosclerosis, with an AUC of 0.589, indicating its potential as a diagnostic biomarker for stable coronary artery disease [Tian et al. DOI:10.3390/molecules26041155].