Basic Information

Symbol
circSMARCA5
RNA Class
circRNA
Alias
SNF2 Related Chromatin Remodeling ATPase 5 HSNF2H HISWI ISWI SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin A5 Sucrose Nonfermenting Protein 2 Homolog WCRF135 SNF2H Sucrose Nonfermenting-Like 5 EC 3.6.4.- EC 3.6.1
Location (GRCh37)
4:144434670-144474749 UCSC Genome Browser
Location (GRCh38)
4:143513517-143553596
UCSC Genome Browser Search in Marker Scope
Host gene
SMARCA5
Host category
mRNA
Forensic tag(s)
Time since deposition estimation Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SMARCA5_0000100 Exon-Exon chr4:144434670-144464799 chr4:143513517-143543646 2449 nt 0.4602
hsa_SMARCA5_0000200 Intron-Intron chr4:144436451-144436845 chr4:143515298-143515692 395 nt 0.3291
hsa_SMARCA5_0000300 Intron-Exon-Intron chr4:144436674-144451679 chr4:143515521-143530526 410 nt 0.3707
hsa_SMARCA5_0000400 Exon-Exon chr4:144438508-144442748 chr4:143517355-143521595 75 nt 0.3733
hsa_SMARCA5_0000500 Exon-Exon chr4:144438508-144449176 chr4:143517355-143528023 176 nt 0.4148
hsa_SMARCA5_0000600 Exon-Exon chr4:144438508-144451679 chr4:143517355-143530526 276 nt 0.3804
hsa_SMARCA5_0000900 Exon-Exon chr4:144442582-144447613 chr4:143521429-143526460 167 nt 0.4192
hsa_SMARCA5_0001000 Exon-Exon chr4:144442582-144451679 chr4:143521429-143530526 236 nt 0.4153
hsa_SMARCA5_0000800 Exon-Exon chr4:144442582-144456117 chr4:143521429-143534964 1016 nt 0.3907
hsa_SMARCA5_0000700 Exon-Exon chr4:144442582-144471257 chr4:143521429-143550104 2841 nt 0.3911
Showing 101 to 110 of 169 entries
Forensic Context

A study in mice demonstrated that the circSMARCA5 promotes angiogenesis by sponging SRSF1 mRNA to regulate VEGF-A [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in human bloodstains demonstrated that the circSMARCA5 exhibited linear degradation over 120 days, with its relative expression negatively correlated with bloodstain age both indoors (r=0.81) and outdoors (r=0.91), and it was incorporated into a mathematical formula for estimating the time since deposition [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. A separate review noted that in human plasma, the circSMARCA5 is lower in patients with more severe coronary atherosclerosis, with an AUC of 0.589, indicating its potential as a diagnostic biomarker for stable coronary artery disease [Tian et al. DOI:10.3390/molecules26041155].