Basic Information

Symbol
circSMARCA5
RNA Class
circRNA
Alias
SNF2 Related Chromatin Remodeling ATPase 5 HSNF2H HISWI ISWI SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin A5 Sucrose Nonfermenting Protein 2 Homolog WCRF135 SNF2H Sucrose Nonfermenting-Like 5 EC 3.6.4.- EC 3.6.1
Location (GRCh37)
4:144434670-144474749 UCSC Genome Browser
Location (GRCh38)
4:143513517-143553596
UCSC Genome Browser Search in Marker Scope
Host gene
SMARCA5
Host category
mRNA
Forensic tag(s)
Time since deposition estimation Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SMARCA5_0002000 Exon-Exon chr4:144446604-144469293 chr4:143525451-143548140 2465 nt 0.3870
hsa_SMARCA5_0002500 Exon-Exon chr4:144447434-144449176 chr4:143526281-143528023 336 nt 0.3542
hsa_SMARCA5_0002800 Exon-Exon chr4:144447434-144449867 chr4:143526281-143528714 312 nt 0.3750
hsa_SMARCA5_0002900 Exon-Exon chr4:144447434-144451679 chr4:143526281-143530526 405 nt 0.3630
hsa_SMARCA5_0002600 Exon-Exon chr4:144447434-144460091 chr4:143526281-143538938 1149 nt 0.3856
hsa_SMARCA5_0003000 Exon-Exon chr4:144447434-144461648 chr4:143526281-143540495 133 nt 0.4060
hsa_SMARCA5_0002700 Exon-Exon chr4:144447434-144464810 chr4:143526281-143543657 1431 nt 0.3878
hsa_SMARCA5_0003100 Exon-Exon chr4:144447434-144465125 chr4:143526281-143543972 120 nt 0.3667
hsa_SMARCA5_0003200 Exon-Exon chr4:144447434-144466736 chr4:143526281-143545583 225 nt 0.4044
hsa_SMARCA5_0003300 Intron-Exon-Intron chr4:144447953-144466146 chr4:143526800-143544993 2696 nt 0.3587
Showing 121 to 130 of 169 entries
Forensic Context

A study in mice demonstrated that the circSMARCA5 promotes angiogenesis by sponging SRSF1 mRNA to regulate VEGF-A [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in human bloodstains demonstrated that the circSMARCA5 exhibited linear degradation over 120 days, with its relative expression negatively correlated with bloodstain age both indoors (r=0.81) and outdoors (r=0.91), and it was incorporated into a mathematical formula for estimating the time since deposition [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. A separate review noted that in human plasma, the circSMARCA5 is lower in patients with more severe coronary atherosclerosis, with an AUC of 0.589, indicating its potential as a diagnostic biomarker for stable coronary artery disease [Tian et al. DOI:10.3390/molecules26041155].