Basic Information

Symbol
circSMARCA5
RNA Class
circRNA
Alias
SNF2 Related Chromatin Remodeling ATPase 5 HSNF2H HISWI ISWI SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin A5 Sucrose Nonfermenting Protein 2 Homolog WCRF135 SNF2H Sucrose Nonfermenting-Like 5 EC 3.6.4.- EC 3.6.1
Location (GRCh37)
4:144434670-144474749 UCSC Genome Browser
Location (GRCh38)
4:143513517-143553596
UCSC Genome Browser Search in Marker Scope
Host gene
SMARCA5
Host category
mRNA
Forensic tag(s)
Time since deposition estimation Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SMARCA5_0006500 Exon-Exon chr4:144464662-144468061 chr4:143543509-143546908 149 nt 0.3893
hsa_SMARCA5_0006600 Exon-Exon chr4:144464662-144468656 chr4:143543509-143547503 388 nt 0.3969
hsa_SMARCA5_0006700 Exon-Exon chr4:144464662-144469293 chr4:143543509-143548140 155 nt 0.3935
hsa_SMARCA5_0006800 Exon-Exon chr4:144464662-144471257 chr4:143543509-143550104 114 nt 0.4123
hsa_SMARCA5_0006900 Exon-Exon chr4:144464666-144465125 chr4:143543513-143543972 265 nt 0.3736
hsa_SMARCA5_0007000 Exon-Exon chr4:144464754-144465125 chr4:143543601-143543972 177 nt 0.3729
hsa_SMARCA5_0007100 Exon-Exon chr4:144465890-144468656 chr4:143544737-143547503 252 nt 0.3889
hsa_SMARCA5_0007200 Exon-Exon chr4:144465890-144471257 chr4:143544737-143550104 111 nt 0.4324
hsa_SMARCA5_0007300 Exon-Exon chr4:144465964-144467200 chr4:143544811-143546047 123 nt 0.4065
hsa_SMARCA5_0007400 Exon-Exon chr4:144466623-144467200 chr4:143545470-143546047 237 nt 0.3924
Showing 151 to 160 of 169 entries
Forensic Context

A study in mice demonstrated that the circSMARCA5 promotes angiogenesis by sponging SRSF1 mRNA to regulate VEGF-A [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in human bloodstains demonstrated that the circSMARCA5 exhibited linear degradation over 120 days, with its relative expression negatively correlated with bloodstain age both indoors (r=0.81) and outdoors (r=0.91), and it was incorporated into a mathematical formula for estimating the time since deposition [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. A separate review noted that in human plasma, the circSMARCA5 is lower in patients with more severe coronary atherosclerosis, with an AUC of 0.589, indicating its potential as a diagnostic biomarker for stable coronary artery disease [Tian et al. DOI:10.3390/molecules26041155].