Basic Information

Symbol
circSMARCA5
RNA Class
circRNA
Alias
SNF2 Related Chromatin Remodeling ATPase 5 HSNF2H HISWI ISWI SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin A5 Sucrose Nonfermenting Protein 2 Homolog WCRF135 SNF2H Sucrose Nonfermenting-Like 5 EC 3.6.4.- EC 3.6.1
Location (GRCh37)
4:144434670-144474749 UCSC Genome Browser
Location (GRCh38)
4:143513517-143553596
UCSC Genome Browser Search in Marker Scope
Host gene
SMARCA5
Host category
mRNA
Forensic tag(s)
Time since deposition estimation Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SMARCA5_0005100 Exon-Exon chr4:144459939-144468061 chr4:143538786-143546908 1036 nt 0.3929
hsa_SMARCA5_0005900 Intron-Exon-Intron chr4:144464632-144465125 chr4:143543479-143543972 299 nt 0.3645
hsa_SMARCA5_0006000 Exon-Exon chr4:144464662-144464810 chr4:143543509-143543657 149 nt 0.3893
hsa_SMARCA5_0006100 Exon-Exon chr4:144464662-144465125 chr4:143543509-143543972 269 nt 0.3792
hsa_SMARCA5_0006200 Exon-Exon chr4:144464662-144466000 chr4:143543509-143544847 380 nt 0.3947
hsa_SMARCA5_0007700 Exon-Exon chr4:144467114-144468021 chr4:143545961-143546868 180 nt 0.3444
hsa_SMARCA5_0001100 Exon-Exon chr4:144445520-144445620 chr4:143524367-143524467 101 nt 0.4455
hsa_SMARCA5_0001200 Exon-Exon chr4:144445520-144449867 chr4:143524367-143528714 670 nt 0.3761
hsa_SMARCA5_0001300 Exon-Exon chr4:144445520-144451679 chr4:143524367-143530526 739 nt 0.3789
hsa_SMARCA5_0001900 Exon-Exon chr4:144446604-144451679 chr4:143525451-143530526 638 nt 0.3683
Showing 11 to 20 of 169 entries
Forensic Context

A study in mice demonstrated that the circSMARCA5 promotes angiogenesis by sponging SRSF1 mRNA to regulate VEGF-A [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in human bloodstains demonstrated that the circSMARCA5 exhibited linear degradation over 120 days, with its relative expression negatively correlated with bloodstain age both indoors (r=0.81) and outdoors (r=0.91), and it was incorporated into a mathematical formula for estimating the time since deposition [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. A separate review noted that in human plasma, the circSMARCA5 is lower in patients with more severe coronary atherosclerosis, with an AUC of 0.589, indicating its potential as a diagnostic biomarker for stable coronary artery disease [Tian et al. DOI:10.3390/molecules26041155].