Basic Information

Symbol
circSMARCA5
RNA Class
circRNA
Alias
SNF2 Related Chromatin Remodeling ATPase 5 HSNF2H HISWI ISWI SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin A5 Sucrose Nonfermenting Protein 2 Homolog WCRF135 SNF2H Sucrose Nonfermenting-Like 5 EC 3.6.4.- EC 3.6.1
Location (GRCh37)
4:144434670-144474749 UCSC Genome Browser
Location (GRCh38)
4:143513517-143553596
UCSC Genome Browser Search in Marker Scope
Host gene
SMARCA5
Host category
mRNA
Forensic tag(s)
Time since deposition estimation Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SMARCA5_0000700 Exon-Exon chr4:144442582-144471257 chr4:143521429-143550104 2841 nt 0.3911
hsa_SMARCA5_0001400 Exon-Exon chr4:144445520-144447613 chr4:143524367-143526460 382 nt 0.3979
hsa_SMARCA5_0001500 Exon-Exon chr4:144445520-144456117 chr4:143524367-143534964 849 nt 0.3852
hsa_SMARCA5_0001600 Exon-Exon chr4:144445520-144457831 chr4:143524367-143536678 1076 nt 0.3838
hsa_SMARCA5_0001700 Exon-Exon chr4:144445520-144466000 chr4:143524367-143544847 1864 nt 0.3922
hsa_chr4_0157500 Intergenic-Intergenic chr4:144445530-144447574 chr4:143524377-143526421 333 nt 0.4054
hsa_SMARCA5_0001800 Exon-Exon chr4:144445551-144457670 chr4:143524398-143536517 884 nt 0.3790
hsa_SMARCA5_0002100 Exon-Exon chr4:144446604-144447613 chr4:143525451-143526460 101 nt 0.3861
hsa_SMARCA5_0002200 Exon-Exon chr4:144446604-144449867 chr4:143525451-143528714 107 nt 0.3925
hsa_SMARCA5_0002300 Exon-Exon chr4:144446604-144457831 chr4:143525451-143536678 101 nt 0.3861
Showing 41 to 50 of 169 entries
Forensic Context

A study in mice demonstrated that the circSMARCA5 promotes angiogenesis by sponging SRSF1 mRNA to regulate VEGF-A [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in human bloodstains demonstrated that the circSMARCA5 exhibited linear degradation over 120 days, with its relative expression negatively correlated with bloodstain age both indoors (r=0.81) and outdoors (r=0.91), and it was incorporated into a mathematical formula for estimating the time since deposition [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. A separate review noted that in human plasma, the circSMARCA5 is lower in patients with more severe coronary atherosclerosis, with an AUC of 0.589, indicating its potential as a diagnostic biomarker for stable coronary artery disease [Tian et al. DOI:10.3390/molecules26041155].