Basic Information

Symbol
circSMARCA5
RNA Class
circRNA
Alias
SNF2 Related Chromatin Remodeling ATPase 5 HSNF2H HISWI ISWI SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin A5 Sucrose Nonfermenting Protein 2 Homolog WCRF135 SNF2H Sucrose Nonfermenting-Like 5 EC 3.6.4.- EC 3.6.1
Location (GRCh37)
4:144434670-144474749 UCSC Genome Browser
Location (GRCh38)
4:143513517-143553596
UCSC Genome Browser Search in Marker Scope
Host gene
SMARCA5
Host category
mRNA
Forensic tag(s)
Time since deposition estimation Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SMARCA5_0003300 Intron-Exon-Intron chr4:144447953-144466146 chr4:143526800-143544993 2696 nt 0.3587
hsa_SMARCA5_0003700 Exon-Exon chr4:144449021-144456117 chr4:143527868-143534964 467 nt 0.3747
hsa_SMARCA5_0003800 Exon-Exon chr4:144449021-144459864 chr4:143527868-143538711 278 nt 0.3633
hsa_SMARCA5_0003900 Exon-Exon chr4:144449021-144460091 chr4:143527868-143538938 156 nt 0.3269
hsa_SMARCA5_0004000 Exon-Exon chr4:144449021-144465125 chr4:143527868-143543972 120 nt 0.3667
hsa_SMARCA5_0003600 Exon-Exon chr4:144449021-144471257 chr4:143527868-143550104 2292 nt 0.3879
hsa_SMARCA5_0004100 Exon-Exon chr4:144449736-144466736 chr4:143528583-143545583 1440 nt 0.3965
hsa_SMARCA5_0004300 Exon-Exon chr4:144456008-144457670 chr4:143534855-143536517 176 nt 0.4034
hsa_SMARCA5_0004400 Exon-Exon chr4:144456008-144461648 chr4:143534855-143540495 243 nt 0.4156
hsa_SMARCA5_0004600 Exon-Exon chr4:144457736-144461648 chr4:143536583-143540495 504 nt 0.4107
Showing 61 to 70 of 169 entries
Forensic Context

A study in mice demonstrated that the circSMARCA5 promotes angiogenesis by sponging SRSF1 mRNA to regulate VEGF-A [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in human bloodstains demonstrated that the circSMARCA5 exhibited linear degradation over 120 days, with its relative expression negatively correlated with bloodstain age both indoors (r=0.81) and outdoors (r=0.91), and it was incorporated into a mathematical formula for estimating the time since deposition [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. A separate review noted that in human plasma, the circSMARCA5 is lower in patients with more severe coronary atherosclerosis, with an AUC of 0.589, indicating its potential as a diagnostic biomarker for stable coronary artery disease [Tian et al. DOI:10.3390/molecules26041155].