Basic Information

Symbol
circSMARCA5
RNA Class
circRNA
Alias
SNF2 Related Chromatin Remodeling ATPase 5 HSNF2H HISWI ISWI SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 5 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin A5 Sucrose Nonfermenting Protein 2 Homolog WCRF135 SNF2H Sucrose Nonfermenting-Like 5 EC 3.6.4.- EC 3.6.1
Location (GRCh37)
4:144434670-144474749 UCSC Genome Browser
Location (GRCh38)
4:143513517-143553596
UCSC Genome Browser Search in Marker Scope
Host gene
SMARCA5
Host category
mRNA
Forensic tag(s)
Time since deposition estimation Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SMARCA5_0004900 Exon-Exon chr4:144459743-144464810 chr4:143538590-143543657 275 nt 0.4145
hsa_SMARCA5_0005000 Exon-Exon chr4:144459743-144466000 chr4:143538590-143544847 231 nt 0.3983
hsa_SMARCA5_0005200 Exon-Exon chr4:144459939-144465125 chr4:143538786-143543972 153 nt 0.4183
hsa_SMARCA5_0005300 Exon-Exon chr4:144460075-144461648 chr4:143538922-143540495 133 nt 0.4060
hsa_SMARCA5_0005400 Exon-Exon chr4:144461516-144469293 chr4:143540363-143548140 1215 nt 0.3885
hsa_SMARCA5_0005500 Intron-Exon-Intron chr4:144464599-144465125 chr4:143543446-143543972 201 nt 0.3483
hsa_SMARCA5_0005600 Intron-Exon-Intron chr4:144464606-144465125 chr4:143543453-143543972 120 nt 0.3667
hsa_SMARCA5_0005700 Intron-Exon-Intron chr4:144464613-144465125 chr4:143543460-143543972 198 nt 0.3535
hsa_SMARCA5_0005800 Intron-Exon-Intron chr4:144464623-144465125 chr4:143543470-143543972 126 nt 0.3651
hsa_SMARCA5_0006300 Exon-Exon chr4:144464662-144466736 chr4:143543509-143545583 494 nt 0.3907
Showing 71 to 80 of 169 entries
Forensic Context

A study in mice demonstrated that the circSMARCA5 promotes angiogenesis by sponging SRSF1 mRNA to regulate VEGF-A [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in human bloodstains demonstrated that the circSMARCA5 exhibited linear degradation over 120 days, with its relative expression negatively correlated with bloodstain age both indoors (r=0.81) and outdoors (r=0.91), and it was incorporated into a mathematical formula for estimating the time since deposition [Wei et al. DOI:10.1016/j.forsciint.2022.111408]. A separate review noted that in human plasma, the circSMARCA5 is lower in patients with more severe coronary atherosclerosis, with an AUC of 0.589, indicating its potential as a diagnostic biomarker for stable coronary artery disease [Tian et al. DOI:10.3390/molecules26041155].