Basic Information
Symbol
circSPG11
RNA Class
circRNA
Alias
SPG11 Vesicle Trafficking Associated, Spatacsin
KIAA1840
Spatacsin
Spastic Paraplegia 11 (Autosomal Recessive)
Colorectal Carcinoma-Associated Protein
Amyotrophic Lateral Sclerosis 5
Spastic Paraplegia 11 Protein
FLJ21439
ALS5
SPG11, Spatacsin Vesicle Trafficking Associated
CMT2X
Location (GRCh37)
15:44876012-44912601
UCSC Genome Browser
Location (GRCh38)
15:44583814-44620403
Host gene
SPG11
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_SPG11_0008900 | Exon-Exon | chr15:44876012-44881612 | chr15:44583814-44589414 | 1123 nt | 0.4622 |
| hsa_SPG11_0013300 | Exon-Exon | chr15:44884529-44912601 | chr15:44592331-44620403 | 2123 nt | 0.4301 |
Forensic Context
A review of the literature indicates that in human patients with Major Depressive Disorder (MDD), the levels of the circSPG11 are altered following antidepressant treatment [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746].