Basic Information
Symbol
circATP9B
RNA Class
circRNA
Alias
ATPase Phospholipid Transporting 9B
ATPIIB
ATPase Phospholipid Transporting 9B (Putative)
Probable Phospholipid-Transporting ATPase IIB
ATPase, Class II, Type 9B
NEO1L
ATPase Type IV, Phospholipid Transporting (P-Type)
Putative Phospholipid-Transporting ATPase IIB
Phospholipid-Transporting ATPase IIB
Macrophage MHC Receptor 1
ATPase Class II Type 9B
EC 7.6.2.1
EC 3.6.3.1
HUSSY-20
EC 3.6.3
ATPASEP
HMMR1
Location (GRCh37)
18:76953183-76974038
UCSC Genome Browser
Location (GRCh38)
18:79193183-79214038
Host gene
ATP9B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ATP9B_0014000 | Exon-Exon | chr18:76953183-76974038 | chr18:79193183-79214038 | 234 nt | 0.4017 |
Forensic Context
A study in mice demonstrated that circATP9B is highly expressed in early-stage hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with impaired cardiac function following acute myocardial infarction [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in humans demonstrated that the circATP9B was significantly downregulated in the peripheral blood mononuclear cells of heart failure patients exhibiting sacubitril/valsartan resistance compared to non-resistant patients, a finding validated by quantitative real-time PCR [Su et al. DOI:10.1016/j.ejphar.2023.175547].