Basic Information
Symbol
circSRPK2
RNA Class
circRNA
Alias
SRSF Protein Kinase 2
SFRS Protein Kinase 2
SFRSK2
Serine/Arginine-Rich Protein-Specific Kinase 2
Serine/Arginine-Rich Splicing Factor Kinase 2
SR-Protein-Specific Kinase 2
SR Protein Kinase 2
EC 2.7.11.1
Serine/Threonine-Protein Kinase SRPK2
Serine Kinase SRPK2
Location (GRCh37)
7:104925456-104937980
UCSC Genome Browser
Location (GRCh38)
7:105285009-105297533
Host gene
SRPK2
Host category
mRNA
Forensic tag(s)
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_SRPK2_0012400 | Intron-Exon-Intron | chr7:104925456-104937980 | chr7:105285009-105297533 | 250 nt | 0.3520 |
Forensic Context
A study in humans demonstrated that the circSRPK2 is a stable circular RNA detectable in body fluids, with its expression levels showing significant differential regulation in various cancer tissues and cell lines, supporting its potential as a diagnostic and prognostic biomarker [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A study in humans identified 736 differentially expressed circRNAs in peripheral blood from ischemic stroke patients, with the circSRPK2 being down-regulated (log2FC=-2.84711) and its host gene identified as SRPK2 [Wei et al. DOI:10.1186/s12883-021-02397-0].