Basic Information
Symbol
circSYNE2
RNA Class
circRNA
Alias
Spectrin Repeat Containing Nuclear Envelope Protein 2
Nesprin-2
NUA
KIAA1011
SYNE-2
NUANCE
Nesp2
Spectrin Repeat Containing, Nuclear Envelope 2
Nucleus And Actin Connecting Element Protein
Nuclear Envelope Spectrin Repeat Protein 2
Synaptic Nuclear Envelope Protein 2
KASH Domain-Containing Protein 2
DKFZP434H2235
KASH2
Nucleus And Actin Connecting Element
Nuclear Envelope Spectrin Repeat-2
Synaptic Nuclei Expressed Gene 2
Nesprin-2 Spectrin Repeats 3-54
Protein NUANCE
Polytrophin
Nesprin 2
Syne-2
EDMD5
TROPH
Location (GRCh37)
14:64595170-64596966
UCSC Genome Browser
Location (GRCh38)
14:64128452-64130248
Host gene
SYNE2
Host category
mRNA
Forensic tag(s)
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_SYNE2_0041100 | Exon-Exon | chr14:64595170-64596966 | chr14:64128452-64130248 | 423 nt | 0.4350 |
Forensic Context
A review of literature on circular RNAs (circRNAs) indicates that the circSYNE2 focuses on the roles of circRNAs in embryogenesis, cell differentiation, and cancer [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A study in humans identified that circSYNE2 is a key target for the treatment of intervertebral disc degeneration, functioning via the miR-302a-3p/HIF1A axis [Huang et al. DOI:10.3390/cells11091381].