Basic Information
Symbol
circTCEB1
RNA Class
circRNA
Alias
Elongin C
TCEB1
SIII
Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C)
RNA Polymerase II Transcription Factor SIII Subunit C
Transcription Elongation Factor B Polypeptide 1
Transcription Elongation Factor B Subunit 1
Elongin 15 KDa Subunit
Elongin-C
SIII P15
Transcription Elongation Factor B (SIII), Polypeptide 1 (15kD, Elongin C)
EloC
Location (GRCh37)
8:74868146-74872053
UCSC Genome Browser
Location (GRCh38)
8:73955911-73959818
Host gene
TCEB1
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_TCEB1_0000900 | Exon-Exon | chr8:74868146-74872053 | chr8:73955911-73959818 | 198 nt | 0.3990 |
Forensic Context
A study in humans demonstrated that circTCEB1 is significantly decreased in peripheral blood of Alzheimer's disease patients and may be used to distinguish them from other dementia cases [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery segments from a postmortem case demonstrated that the expression of the circTCEB1 was validated by qRT-PCR and showed differential expression across arterial segments, suggesting a pathological role in coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].