Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0000100 Exon-Exon chr2:171847333-171902872 chr2:170990823-171046362 250 nt 0.3080
hsa_TLK1_0001000 Exon-Exon chr2:171853163-171917666 chr2:170996653-171061156 1794 nt 0.3913
hsa_TLK1_0002000 Exon-Exon chr2:171862657-171863573 chr2:171006147-171007063 488 nt 0.3832
hsa_TLK1_0002100 Exon-Exon chr2:171862657-171867964 chr2:171006147-171011454 570 nt 0.3772
hsa_TLK1_0002200 Exon-Exon chr2:171862657-171902872 chr2:171006147-171046362 924 nt 0.3820
hsa_TLK1_0003100 Exon-Exon chr2:171862657-171917666 chr2:171006147-171061156 1574 nt 0.3907
hsa_TLK1_0003300 Exon-Exon chr2:171862657-171974367 chr2:171006147-171117857 1765 nt 0.3960
hsa_TLK1_0004000 Exon-Exon chr2:171863310-171939362 chr2:171006800-171082852 1340 nt 0.3903
hsa_TLK1_0004200 Exon-Exon chr2:171867883-171871458 chr2:171011373-171014948 180 nt 0.3611
hsa_TLK1_0004300 Exon-Exon chr2:171867883-171884915 chr2:171011373-171028405 247 nt 0.3563
Showing 1 to 10 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].