Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0005100 Exon-Exon chr2:171867883-171974367 chr2:171011373-171117857 1604 nt 0.4102
hsa_TLK1_0005200 Intron-Exon-Intron chr2:171869680-171872810 chr2:171013170-171016300 250 nt 0.4320
hsa_TLK1_0005400 Intron-Exon-Intron chr2:171871361-171879507 chr2:171014851-171022997 224 nt 0.4152
hsa_TLK1_0005500 Intron-Exon-Intron chr2:171871361-171879639 chr2:171014851-171023129 356 nt 0.4157
hsa_TLK1_0005600 Exon-Exon chr2:171871361-171902872 chr2:171014851-171046362 98 nt 0.3776
hsa_TLK1_0005700 Exon-Exon chr2:171871361-171906684 chr2:171014851-171050174 209 nt 0.3397
hsa_TLK1_0005800 Intron-Exon-Intron chr2:171871361-171906713 chr2:171014851-171050203 889 nt 0.3937
hsa_TLK1_0005900 Intron-Exon-Intron chr2:171871361-171922529 chr2:171014851-171066019 98 nt 0.3776
hsa_TLK1_0006000 Exon-Exon chr2:171871361-171939362 chr2:171014851-171082852 98 nt 0.3776
hsa_TLK1_0006100 Exon-Exon chr2:171871361-171974367 chr2:171014851-171117857 244 nt 0.4180
Showing 111 to 120 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].