Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0009300 Exon-Exon chr2:171884849-171939362 chr2:171028339-171082852 208 nt 0.4135
hsa_TLK1_0008500 Intron-Exon-Intron chr2:171884849-171947739 chr2:171028339-171091229 250 nt 0.2960
hsa_TLK1_0008600 Intron-Exon-Intron chr2:171884849-171948737 chr2:171028339-171092227 250 nt 0.3040
hsa_TLK1_0008700 Intron-Exon-Intron chr2:171884849-171948777 chr2:171028339-171092267 250 nt 0.2800
hsa_TLK1_0009400 Exon-Exon chr2:171884849-171974367 chr2:171028339-171117857 125 nt 0.4560
hsa_chr2_0268700 Intergenic-Intergenic chr2:171889614-171889962 chr2:171033104-171033452 349 nt 0.3954
hsa_TLK1_0009500 Intron-Exon-Intron chr2:171901572-171902872 chr2:171045062-171046362 1301 nt 0.3713
hsa_TLK1_0009600 Intron-Exon-Intron chr2:171901572-171906684 chr2:171045062-171050174 111 nt 0.3063
hsa_TLK1_0010200 Exon-Exon chr2:171902684-171902872 chr2:171046174-171046362 189 nt 0.4127
hsa_TLK1_0010400 Exon-Exon chr2:171902684-171911682 chr2:171046174-171055172 90 nt 0.4111
Showing 141 to 150 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].