Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0011000 Intron-Exon-Intron chr2:171905698-171906460 chr2:171049188-171049950 763 nt 0.3316
hsa_chr2_0268900 Intergenic-Intergenic chr2:171906200-171906455 chr2:171049690-171049945 256 nt 0.3516
hsa_TLK1_0011200 Exon-Exon chr2:171906324-171906684 chr2:171049814-171050174 248 nt 0.3669
hsa_TLK1_0011300 Exon-Exon chr2:171906324-171911682 chr2:171049814-171055172 227 nt 0.4141
hsa_TLK1_0011400 Exon-Exon chr2:171906324-171917666 chr2:171049814-171061156 213 nt 0.4225
hsa_TLK1_0011500 Exon-Exon chr2:171906324-171939330 chr2:171049814-171082820 40 nt 0.3750
hsa_TLK1_0011600 Exon-Exon chr2:171906324-171939362 chr2:171049814-171082852 396 nt 0.3838
hsa_TLK1_0011100 Intron-Exon-Intron chr2:171906324-171948737 chr2:171049814-171092227 250 nt 0.3320
hsa_TLK1_0011700 Exon-Exon chr2:171906324-171974367 chr2:171049814-171117857 256 nt 0.4414
hsa_TLK1_0011800 Exon-Exon chr2:171906574-171913076 chr2:171050064-171056566 390 nt 0.3923
Showing 161 to 170 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].