Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0011900 Intron-Intron chr2:171907676-171908668 chr2:171051166-171052158 993 nt 0.3897
hsa_TLK1_0012200 Exon-Exon chr2:171910271-171910665 chr2:171053761-171054155 211 nt 0.3602
hsa_TLK1_0012100 Exon-Exon chr2:171910271-171913076 chr2:171053761-171056566 279 nt 0.4265
hsa_TLK1_0012300 Exon-Exon chr2:171910271-171914707 chr2:171053761-171058197 99 nt 0.3838
hsa_TLK1_0012500 Exon-Exon chr2:171910271-171939362 chr2:171053761-171082852 288 nt 0.4063
hsa_TLK1_0012000 Intron-Exon-Intron chr2:171910271-171948737 chr2:171053761-171092227 250 nt 0.3200
hsa_TLK1_0012600 Exon-Exon chr2:171910271-171974367 chr2:171053761-171117857 360 nt 0.4278
hsa_TLK1_0012800 Exon-Exon chr2:171911593-171914707 chr2:171055083-171058197 233 nt 0.4335
hsa_TLK1_0012900 Exon-Exon chr2:171911593-171917666 chr2:171055083-171061156 82 nt 0.4268
hsa_TLK1_0013000 Exon-Exon chr2:171911593-171939362 chr2:171055083-171082852 90 nt 0.4111
Showing 171 to 180 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].